What is the consequence of hypersecretion of growth hormone after puberty?

The consequence of hypersecretion of growth hormone after puberty is acromegaly. This condition arises from an excess of growth hormone, usually due to a benign tumor of the pituitary gland. After puberty, when the growth plates have closed, excess growth hormone does not lead to increased height, as seen in gigantism, but instead causes the bones and tissues to thicken.

Patients with acromegaly commonly experience enlarged hands and feet, facial changes such as a protruding jaw, and thickening of the skin. The effects can also include various metabolic disturbances, such as insulin resistance, due to the influence of excess growth hormone on other hormonal pathways.

The other conditions listed are not the correct consequence of hypersecretion of growth hormone after puberty, as acromegaly specifically relates to the physiological changes that occur post-puberty rather than during growth periods.