What defines adrenal insufficiency?

Adrenal insufficiency is characterized by the body's inability to produce adequate amounts of adrenal hormones, particularly cortisol and, in some cases, aldosterone. This occurs due to dysfunction of the adrenal glands, which may be caused by various factors, including autoimmune conditions, infections, or adrenal gland damage.

In the context of this condition, insufficient hormone production can lead to symptoms such as fatigue, weight loss, low blood pressure, and electrolyte imbalances due to inadequate aldosterone. Early recognition and treatment are critical, as adrenal insufficiency can lead to an adrenal crisis if not properly managed, which is a life-threatening situation requiring urgent medical intervention.

Overall, the key defining aspect of adrenal insufficiency is the lack of sufficient hormone production by the adrenal glands, making the correct answer directly aligned with the definition of the condition.